I-2-Methylbenzophenone ene-CAS 131-58-8

Isithombe Esifakiwe se-2-Methylbenzophenone Ne-CAS 131-58-8

I-CAS:131-58-8

I-MF:C14H12O

I-MW:196.24

Inombolo ye-EINECS:205-032-0

Amagama afanayo:2-methylphenyl)phenyl-methanon; i-Benzophenone, 2-methyl-; 2-PHENYL CARBONYL TOLUENE; 2-PHENYL TOLYL KETONE; 2-METHYLBENZOPHENONE; i-PHENYL O-TOLYL KETONE; i-PHENYL 2-TOLYL KETONE; 2-Methylbenzophenone

Shiya Umlayezo Wakho

Imininingwane Yomkhiqizo

Landa

Amathegi Omkhiqizo

Iyini i-2-Methylbenzophenone ene-CAS 131-58-8?

I-2-Methylbenzophenone iyinhlanganisela ye-benzophenone, okuyikhemikhali enhle ebaluleke kakhulu. Ngesikhathi esifanayo, ama-ketone nawo ayizakhiwo eziyinhloko zama-molecule amaningi e-organic, njengezinto ezisebenzayo, amakha kanye nama-molecule ezidakamizwa. Ama-ketone anephunga elimnandi ayizakhi zokwakha ezibaluleke kakhulu zokwenziwa ekwakhiweni kwezinto eziphilayo, ezikhona kabanzi ezakhiweni eziyinhloko zemikhiqizo yemvelo futhi zisetshenziswa kabanzi kuma-compounds asebenzayo ngokwezinto eziphilayo.

Imininingwane

Into	Okujwayelekile
Ukubukeka	Uketshezi oluphuzi olukhanyayo olungenambala
Ukuhlolwa	≥99.0%
Amanzi	≤0.20%

Isicelo

Ngaphansi kokuvikelwa kwegesi engasebenzi, i-2-methylphenylsulfonylhydrazide (1.1 mmol), i-benzonitrile (1.0 mmol), i-palladium catalyst (2 mol %) kanye ne-biquinoline (bq, 3 mol %) zahlakazeka ku-solvent ephilayo (2 mL) ), kwabe sekufakwa i-H2O (2 mmol), kwathi izinga lokushisa laphakanyiswa laya ku-80°C amahora ayi-6. Ngemuva kwalokho isixazululo sokusabela sakhishwa kathathu nge-Et2O (5 mL), izigaba zezinto eziphilayo zahlanganiswa, kwathi i-solvent yomiswa nge-spin ngaphansi kwengcindezi encishisiwe. Umkhiqizo oluhlaza otholiwe wafakwa ku-chromatography yekholomu kukholamu yejeli ye-silica (300-400 mesh), kanti ama-eluents ayeyi-petroleum ether , ukuthola umkhiqizo oqondiwe i-2-methylbenzophenone. Izakhiwo zamakhemikhali Uketshezi olungenambala noma oluphuzi olukhanyayo olukhanyayo. Iphuzu lokuncibilika licishe libe ngu-134°C. Sebenzisa njenge-medicate intermediate yemithi.