2019 Ikhwalithi ephezulu Ikhwalithi ephezulu 93-02-7 2, 5-Dimethoxybenzaldehyde CAS 93 02 7

Esikuphishekelayo kwaphakade isimo sengqondo "sokubheka imakethe, bheka isiko, bheka isayensi" kanye nethiyori "yekhwalithi eyisisekelo, nokholo ekuqaleni kanye nokuphatha okuthuthukile" ngo-2019 Ikhwalithi Ephezulu Yekhwalithi 93-02-72, 5-Dimethoxybenzaldehyde CAS 93 02 7, Ngakho-ke, singahlangabezana nemibuzo ehlukene evela kubathengi abahlukene. Kufanele uthole ikhasi lethu lewebhu ukuze uhlole ulwazi olwengeziwe oluvela emikhiqizweni yethu.
Esiphishekelayo saphakade isimo sengqondo "sokubheka imakethe, bheka isiko, bheka isayensi" kanye nethiyori "yekhwalithi eyisisekelo, nokholo ekuqaleni kanye nokuphatha okuthuthukile"I-CAS 93 02 7 kanye ne-2 5-Dimethoxybenzaldehyde, Izinhlobo eziningi zokuthengiswayo okuhlukile ziyatholakala ukuthi uzikhethele mathupha, ungenza ukuthenga endaweni eyodwa lapha. Futhi ama-oda enziwe ngezifiso ayamukeleka. Ibhizinisi langempela ukuthola isimo sokuwina, uma kungenzeka, singathanda ukunikeza ukwesekwa okwengeziwe kumakhasimende. Siyakwamukela bonke abathengi abahle baxhumane nathi imininingwane yokuthengiswayo !!

I-2,5-Dimethoxybenzaldehyde iyimpushana yekristalu ephuzi ekhanyayo enesisindo semolekyuli esingu-166.18 kanye nephoyinti elibilayo elingu-146°C. Incibilika kuzincibilikisi zemvelo njenge-ethanol ne-ether. Isetshenziswa kakhulu njengendawo ephakathi yemithi.

Ngaphezu kokuthi i-oxidized noma yehliselwe ku-2,5-dimethoxybenzoic acid, i-benzonitrile noma i-benzyl alcohol,2,5-dimethoxybenzaldehydengokwayo futhi inenani lesicelo eliyingqayizivele. Ngokusabela ngezinto ezinezinhlobo ezahlukene zamaqembu asebenzayo, ama-molecule ezidakamizwa anezakhiwo ezahlukene kanye nemiphumela ehlukene angatholakala. Isifo sikaParkinson (PD) yisifo esivamile se-neurodeergenerative, futhi izimpawu zaso eziyinhloko zomtholampilo zihlanganisa ukundindizela kwemisipha, ukuqina, ubunzima bokunyakaza, ukuma komzimba kanye nokuphazamiseka kokulingana kokunyakaza. Ukuthuthuka okuqhubekayo kuzoholela ekuqashelweni, ekuboneni, ekuphazamisekeni kwenkumbulo kanye nokuwohloka komqondo okusobala. Njengamanje, ukwelashwa kwe-PD ikakhulukazi kuhlanganisa ukwelapha izidakamizwa, ukwelashwa ngokuhlinzwa kanye nokwelashwa ngofuzo. Ekwelashweni kwezidakamizwa, i-phenamidine itholakale inomthelela omuhle ku-PD, enobuthi obuphansi nokuphepha okuhle, futhi ukuhlanganiswa kwe-phenamidine kudinga ukusetshenziswa kwe-2,5-dimethoxybenzaldehyde njengento yokuqala.

Ngokwendlela yokuhlanganisa ebikwe ezincwadini,2,5-dimethoxybenzaldehydeitholakala ikakhulukazi ngokusabela i-1,4-dimethoxybenzene nge-ejenti ye-formylation. Ama-Formylation agents ahlanganisa (1) ingxube ye-1,1-dichloromethyl ether ne-titanium tetrachloride; (2) ingxube ye-N,N-dimethylformamide ne-phosphorus oxychloride, ingxube ye-N,N-dimethylformamide ne-oxalyl chloride; (3) ingxube ye-N,N-dimethylformamide ne-thionyl chloride noma ingxube ye-urotropine ne-magnesium chloride. Nokho, lezi zindlela zidinga ukusetshenziswa kwenani elikhulu le-titanium tetrachloride, i-phosphorus oxychloride noma i-thionyl chloride. Lawa ma-reagents azinzile futhi abola kalula, futhi inani elikhulu legesi le-hydrochloric acid likhishwa ngesikhathi sokusabela, elingahambisani nemvelo futhi linezidingo eziphezulu zenqubo yokusebenza.

Kuphakanyiswe indlela entsha yokuhlanganisa. Le ndlela isebenzisa i-1,4-dimethoxybenzene kanye ne-formaldehyde njengezinto zokusetshenziswa, futhi yenza ukuhlangana kwe-photooxidative lapho kukhona umoya-mpilo kanye ne-catalyst ngaphansi kwe-irradiation yokukhanya eluhlaza okwesibhakabhaka ukuze kuhlanganiswe kahle i-2,5-dimethoxybenzaldehyde. Le ndlela isebenzisa umoya-mpilo noma umoya njenge-oxidant, ayikhiqizi igesi ene-asidi, futhi ihambisana nemvelo. Ngaphezu kwalokho, le ndlela isebenzisa i-cobalt eshibhile njenge-catalyst, ephansi ngentengo futhi ifanele ukusetshenziswa kwezimboni.

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Esikuphishekelayo kwaphakade isimo sengqondo "sokubheka imakethe, bheka isiko, bheka isayensi" kanye nethiyori "yekhwalithi eyisisekelo, nokholo ekuqaleni kanye nokuphatha okuthuthukile" ngo-2019 Ikhwalithi Ephezulu Yekhwalithi 93-02-72, 5-Dimethoxybenzaldehyde CAS 93 02 7, Ngakho-ke, singahlangabezana nemibuzo ehlukene evela kubathengi abahlukene. Kufanele uthole ikhasi lethu lewebhu ukuze uhlole ulwazi olwengeziwe oluvela emikhiqizweni yethu.
2019 Ikhwalithi ephezuluI-CAS 93 02 7 kanye ne-2 5-Dimethoxybenzaldehyde, Izinhlobo eziningi zokuthengiswayo okuhlukile ziyatholakala ukuthi uzikhethele mathupha, ungenza ukuthenga endaweni eyodwa lapha. Futhi ama-oda enziwe ngezifiso ayamukeleka. Ibhizinisi langempela ukuthola isimo sokuwina, uma kungenzeka, singathanda ukunikeza ukwesekwa okwengeziwe kumakhasimende. Siyakwamukela bonke abathengi abahle baxhumane nathi imininingwane yokuthengiswayo !!