Ifektri yaseShayina yomkhiqizi weMithi Ephakathi, Umhlinzeki WeMithi Ephakathi, Umhlinzeki We-Prilocaine Powder Webanga Eliphezulu
Imivuzo yethu ukunciphisa amanani okuthengisa, ithimba lemali engenayo eliguquguqukayo, i-QC ekhethekile, amafektri aqinile, izinsizakalo zekhwalithi ephezulu ze-China Factory for Pharmaceutical Intermediate Manufacturer, Pharmaceutical Intermediate, High Grade Prilocaine Powder Supplier, singaxazulula izinkinga zamakhasimende ethu ngokushesha futhi senze inzuzo kumakhasimende ethu. Uma udinga inkampani enhle kakhulu nekhwalithi ephezulu, sicela usikhethe, ngiyabonga!
Imivuzo yethu ukunciphisa amanani okuthengisa, ithimba lemali engenayo eliguqukayo, i-QC ekhethekile, amafektri aqinile, izinsizakalo zekhwalithi ephezulu zeLtd., Inkampani yezobuchwepheshe iWuhan Jingkang, Inkampani yethu ibheka "amanani afanele, isikhathi sokukhiqiza esisebenzayo kanye nensizakalo enhle yangemva kokuthengisa" njengesimiso sethu. Sithemba ukubambisana namakhasimende amaningi ukuze kuthuthukiswe futhi kuzuze ngokubambisana. Siyakwamukela abathengi abangaba khona ukuthi basithinte.
2,5-Dimethoxybenzaldehydeiyimpuphu ephuzi ekhanyayo ekristalu enesisindo sama-molecule esingu-166.18 kanye nephuzu lokubilisa elingu-146°C. Iyancibilika ezinyibilikisini eziphilayo ezifana ne-ethanol ne-ether. Isetshenziswa kakhulu njenge-medicine intermediate.
| ITEM | IZINGA |
| Ukubukeka | Okuqinile okumpunga kuya kokuphuzi |
| I-NMR | Ukuthobela |
| Ubumsulwa | >98% |
| Indawo yokuncibilika | 46-48 °C (ngokukhanya) |
| Okuqukethwe kwamanzi | <0.5% |
Ngaphezu koku-oxidized noma ukuncishiswa kube yi-2,5-dimethoxybenzoic acid, i-benzonitrile noma i-benzyl alcohol,2,5-dimethoxybenzaldehydengokwayo nayo inenani eliyingqayizivele lokusebenza. Ngokusabela ezintweni ezinezinhlobo ezahlukene zamaqembu asebenzayo, ama-molecule emithi anezakhiwo ezahlukene nemiphumela ehlukene angatholakala. Isifo sikaParkinson (PD) yisifo esivamile sokuwohloka kwemizwa, futhi izimpawu zaso eziyinhloko zokwelapha zifaka phakathi ukuthuthumela kwemisipha, ukuqina, ubunzima bokunyakaza, ukuma komzimba kanye nokuphazamiseka kokulinganisela kokunyakaza. Intuthuko eyengeziwe izophinde iholele ekuqaphelweni, ekuboneni, ekuphazamisekeni kwenkumbulo kanye nokuwohloka komqondo okusobala. Njengamanje, ukwelashwa kwe-PD kuhlanganisa kakhulu ukwelashwa ngemithi, ukwelashwa ngokuhlinzwa kanye nokwelashwa ngezakhi zofuzo. Ekwelashweni ngemithi, i-phenamidine itholakale inomphumela omuhle ku-PD, enobuthi obuphansi kanye nokuphepha okuhle, kanti ukwenziwa kwe-phenamidine kudinga ukusetshenziswa kwe2,5-dimethoxybenzaldehydenjengento yokuqala.
Ngokwendlela yokuhlanganisa ebikwe ezincwadini,2,5-dimethoxybenzaldehydeItholakala kakhulu ngokusabela i-1,4-dimethoxybenzene nge-ejenti ye-formylation. Ama-formylation agents afaka phakathi (1) ingxube ye-1,1-dichloromethyl ether kanye ne-titanium tetrachloride; (2) ingxube ye-N,N-dimethylformamide kanye ne-phosphorus oxychloride, ingxube ye-N,N-dimethylformamide kanye ne-oxalyl chloride; (3) ingxube ye-N,N-dimethylformamide kanye ne-thionyl chloride noma ingxube ye-urotropine kanye ne-magnesium chloride. Kodwa-ke, lezi zindlela zidinga ukusetshenziswa kwenani elikhulu le-titanium tetrachloride, i-phosphorus oxychloride noma i-thionyl chloride. Lawa ma-reagents awazinzile futhi abola kalula, futhi inani elikhulu legesi ye-hydrochloric acid liyakhishwa ngesikhathi sokusabela, okungenabo ubungani bemvelo futhi kunezidingo eziphezulu zenqubo yokusebenza.
Kuphakanyiswe indlela entsha yokwenza izinto. Le ndlela isebenzisa i-1,4-dimethoxybenzene kanye ne-formaldehyde njengezinto zokusetshenziswa, futhi yenza ukusabela kokuhlanganisa nge-photooxidative lapho kukhona umoya-mpilo kanye ne-catalyst ngaphansi kokukhanya okuluhlaza okwesibhakabhaka ukuze kuhlanganiswe kahle i-2,5-dimethoxybenzaldehyde. Le ndlela isebenzisa umoya-mpilo noma umoya njenge-oxidant, ayikhiqizi igesi ene-acidic, futhi inobungani nemvelo. Ngaphezu kwalokho, le ndlela isebenzisa i-cobalt eshibhile njenge-catalyst, enentengo ephansi futhi efanelekile ukusetshenziswa kwezimboni.
25kgs/isigubhu, 9tons/20'container
25kgs/isikhwama, 20tons/20'container
Imivuzo yethu ukunciphisa amanani okuthengisa, ithimba lemali engenayo eliguquguqukayo, i-QC ekhethekile, amafektri aqinile, izinsizakalo zekhwalithi ephezulu ze-China Factory for Pharmaceutical Intermediate Manufacturer, Pharmaceutical Intermediate, High Grade Prilocaine Powder Supplier, singaxazulula izinkinga zamakhasimende ethu ngokushesha futhi senze inzuzo kumakhasimende ethu. Uma udinga inkampani enhle kakhulu nekhwalithi ephezulu, sicela usikhethe, ngiyabonga!
Ifektri yaseShayina yeInkampani yezobuchwepheshe iWuhan Jingkang, Ltd, Inkampani yethu ibheka "amanani afanele, isikhathi sokukhiqiza esisebenzayo kanye nensizakalo enhle yangemva kokuthengisa" njengesimiso sethu. Sithemba ukubambisana namakhasimende amaningi ukuze kuthuthukiswe futhi kuzuze ngokubambisana. Siyakwamukela abathengi abangaba khona ukuthi basithinte.
