I-Cinchonine CAS 118-10-5

I-CAS:118-10-5

I-Molecular Formula:I-C19H22N2O

Isisindo se-Molecular:294.39

I-EINECS:204-234-6

Omqondofana:(+)-cinconine; (8r,9s) -cinchonine; (9s)-cinchonan-9-o; (9S)-Cinchonan-9-ol; (+)-CINCHONINE; I-CINCHONINE; I-CINCONAN-9-OL,(9S)-; I-Cinchonine, 98+%; I-Cinchonine dihydrate monohydrochloride; Isixazululo seCinchonine [sokufutha]; (9S)-Cinconan-9-ol

Shiya Umlayezo Wakho

Imininingwane Yomkhiqizo

Landa

Omaka bomkhiqizo

Iyini i-Cinchonine CAS 118-10-5?

I-Cinchonine iwuhlobo lwe-quinoline alkaloid, uhlobo lwe-alkaloid olutholakala ku-cinchona alkaloids, eyaziwa nangokuthi i-cinchonine noma i-cinchona alkaloids ebuthakathaka. I-stereoisomer ye-cinchonidine. I-Xinkening iyi-alkaloid enokuqukethwe okuphezulu emagxolweni egxolo le-cinchona, ngaphandle kwe-quinine.

Ukucaciswa

Into	Ukucaciswa
Izimo zokugcina	Ukushisa Kwegumbi
Ukuminyana	1.0863 (isilinganiso esinzima)
Iphoyinti lokuncibilika	260-263 °C
pKa	5.85, 9.92(ku-25℃)
MW	294.39
Iphuzu elibilayo	436.16°C (isilinganiso esinzima)

Isicelo

Umthelela weCinchonine ekukhuleni kweseli yesimila waphenywa, futhi kwatholakala ukuthi iCinchonine ingakhuthaza i-tumor cell apoptosis. Imiphumela yokuhlola engenhla ibonisa ukuthi i-Cinchonine ingavimbela ukukhula kweseli yesimila, ikhuthaze i-apoptosis yakuqala yamathumba, ithuthukise ukuvezwa kwezici ze-pro apoptotic, futhi ivimbele ukuvezwa kwezinto ezilwa ne-apoptotic. I-Xinkening kulindeleke ukuthi isetshenziswe ezindaweni ezilwa nesimila ngokuzayo.