I-Madecassic acid ene-CAS 18449-41-7

I-MF:C30H48O6

Isisindo sama-molecule:504.71

Ukubukeka:Impuphu

Igama elifanayo:(2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oicacid;MADECASSICACID;Urs-12-en-28-oicacid,2,3,6,23-tetrahydroxy-,(2.alpha.,3.beta.,4.alpha.,6.beta.)-

Shiya Umlayezo Wakho

Imininingwane Yomkhiqizo

Landa

Amathegi Omkhiqizo

Iyini i-Madecassic acid ene-CAS 18449-41-7?

I-Madecassic acid iyi-triterpenoid etholakale ku-C. asiatica futhi inemisebenzi eyahlukahlukene yebhayoloji. Ivimbela ukukhiqizwa kwe-nitric oxide (NO) okubangelwa yi-LPS, i-prostaglandin E2 (PGE2; Inombolo Yento 14010), i-TNF-α, i-IL-1β, kanye ne-IL-6 kuma-macrophage e-RAW 264.7 uma isetshenziswa ekugxilweni okungu-150 μg/ml. I-Madecassic acid (0.05 kanye no-0.1% ekudleni) yehlisa amazinga e-plasma e-fibrinogenin kanye ne-triglycerides, kanye namazinga enhliziyo nezinso ezinhlobo ze-oxygen ezisabelayo (ROS), kumodeli yegundane yesifo sikashukela esibangelwa yi-streptozotocin (STZ; Inombolo Yento 13104). Yehlisa ukukhula kwesimila kumodeli yomdlavuza wekoloni ye-murine ye-CT26 ngendlela encike kumthamo.

Imininingwane ye-Madecassic acid ene-CAS 18449-41-7

I-CAS	18449-41-7
Amagama	I-Madecassic acid
Ukubukeka	Impuphu
Ubumsulwa	98%
MF	C30H48O6
Ibanga	Ukudla $ Ibanga Lezokwelapha
Iphakheji	25kgs/isikhwama, 20tons/20'container
I gama le-brand	I-Unilong

Ukusetshenziswa kwe-Madecassic acid ne-CAS 18449-41-7

I-Madecassic Acid iyi-terpenoid enohlaka lwe-ursane oluhlukaniswe ne-Centella asiatica. I-Madecassic Acid ibonisa izakhiwo zokulwa nokuvuvukala ngenxa yokuvinjelwa kwe-iNOS, i-COX-2, i-TNF-alpha, i-IL-1beta, kanye ne-IL-6 ngokunciphisa ukusebenza kwe-NF-kappaB kumaseli e-RAW 264.7 macrophage.