I-Madecassic acid ene-CAS 18449-41-7

MF:I-C30H48O6

Isisindo samangqamuzana:504.71

Ukubukeka:Impushana

Igama elifanayo:(2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oicacid;MADECASSICACID;Urs-12-en-28-oicacid,2,3,6,23- i-tetrahydroxy-,(2.alpha.,3.beta.,4.alpha.,6.beta.)-

Shiya Umlayezo Wakho

Imininingwane Yomkhiqizo

Landa

Omaka bomkhiqizo

Iyini i-Madecassic acid nge-CAS 18449-41-7?

I-Madecassic acid iyi-triterpenoid etholakale ku-C. asiatica futhi inemisebenzi ehlukahlukene yebhayoloji. Ivimbela ukukhiqizwa kwe-LPS okwenziwe yi-nitric oxide (NO), i-prostaglandin E2 (PGE2; Into No. 14010), i-TNF-α, i-IL-1β, ne-IL-6 ku-RAW 264.7 macrophages uma isetshenziswe ekuhlanganiseni kwe-150 μg / ml . I-Madecassic acid (i-0.05 kanye ne-0.1% ekudleni) inciphisa amazinga e-plasma e-fibrinogenin ne-triglycerides, kanye namazinga enhliziyo nezinso zezinhlobo ze-oxygen esebenzayo (ROS), kumodeli yegundane yesifo sikashukela esibangelwa i-streptozotocin (STZ; Into No. 13104 ). Yehlisa ukukhula kwesimila kumodeli yomdlavuza wekoloni ye-CT26 murine ngendlela encike kumthamo.

Ukucaciswa kwe-Madecassic acid nge-CAS 18449-41-7

I-CAS	18449-41-7
Amagama	I-Madecassic acid
Ukubukeka	Impushana
Ubumsulwa	98%
MF	I-C30H48O6
Ibanga	Ukudla $ Ibanga Lezokwelapha
Iphakheji	25kgs/isikhwama,20tons/20'container
I gama le-brand	I-unilong

Ukusetshenziswa kwe-Madecassic acid nge-CAS 18449-41-7

I-Madecassic Acid iyi-terpenoid enohlaka lwamathambo e-ursane ahlukanisiwe ne-Centella asiatica. I-Madecassic Acid ibonisa izici zokulwa nokuvuvukala njengomphumela we-iNOS, COX-2, TNF-alpha, IL-1beta, kanye ne-IL-6 inhibition ngokwehlisa ukulawulwa kokusebenza kwe-NF-kappaB kumaseli e-macrophage angu-RAW 264.7.