I-Rifamycin S CAS 13553-79-2

I-CAS:13553-79-2

I-Molecular Formula:I-C37H45NO12

Isisindo se-Molecular:2695.75

I-EINECS:236-938-4

Omqondofana:I-Rifaximin ukungcola E (EP); I-Rifaximin Impurity 5 (Rifaximin EP Ukungcola E); I-Rifamycin, i-1,4-dideoxy-1,4-dihydro-1,4-dioxo-; I-Rifaximin EP Ukungcola E; i-rifamycin; Rifamycin S CRS; I-Rifamycin Impurity 2(Rifamycin EP Ukungcola B) (Rifamycin S); I-Rifamycin S USP/EP/BP

Shiya Umlayezo Wakho

Imininingwane Yomkhiqizo

Landa

Omaka bomkhiqizo

Iyini i-Rifamycin S CAS 13553-79-2?

I-Rifamycin S iwumkhiqizo wesizukulwane sesithathu wesigaba semithi ye-rifampicin, esebenza ngempumelelo ephezulu kanye nomsebenzi wokulwa namagciwane obanzi. Izwela kakhulu kumagciwane ahlukahlukene ajwayelekile amelana nemithi. I-Lipomycin B idlula i-oxidation, inciphe, kanye ne-hydrolysis ukuze ikhiqize i-rifampicin sodium.

Ukucaciswa

Into	Ukucaciswa
Iphuzu elibilayo	700.89°C (isilinganiso esinzima)
Ukuminyana	1.2387 (isilinganiso esinzima)
Iphoyinti lokuncibilika	179-181°C (dec.)
pKa	3.85±0.70(Kubikezelwe)
ukumelana	1.6630 (isilinganiso)
Izimo zokugcina	-20°C Isiqandisi

Isicelo

I-Rifamycin S isetshenziswa njengendawo emaphakathi yemithi ukuvimbela umsebenzi webhaktheriya i-RNA polymerase. Ukuvimbela ukuhlanganiswa kwe-RNA yebhaktheriya, ekugcineni kuvimbele ukuhlanganiswa kwamaprotheni adingwa amagciwane, okuholela ekufeni kwebhaktheriya futhi kubonise imiphumela ye-bactericidal.