I-Rifamycin S CAS 13553-79-2

Isithombe Esifakiwe se-Rifamycin S CAS 13553-79-2

I-CAS:13553-79-2

Ifomula Yamamolekyuli:C37H45NO12

Isisindo sama-molecule:2695.75

I-EINECS:236-938-4

Amagama afanayo:Ukungcola kwe-Rifaximin E (EP); Ukungcola kwe-Rifaximin 5 (Ukungcola kwe-Rifaximin EP E); I-Rifamycin, 1,4-dideoxy-1,4-dihydro-1,4-dioxo-; Ukungcola kwe-Rifaximin EP E; i-rifamycin; I-Rifamycin S CRS; Ukungcola kwe-Rifamycin 2 (Ukungcola kwe-Rifamycin EP B) (i-Rifamycin S); I-Rifamycin S USP/EP/BP

Shiya Umlayezo Wakho

Imininingwane Yomkhiqizo

Landa

Amathegi Omkhiqizo

Iyini i-Rifamycin S CAS 13553-79-2?

I-Rifamycin S ingumkhiqizo wesizukulwane sesithathu wesigaba semithi ye-rifampicin, enekhono eliphezulu kanye nomsebenzi wokulwa namagciwane we-spectrum ebanzi. Inokuzwela okuphezulu kumagciwane ahlukahlukene avamile emithini amelana nemithi. I-Lipomycin B idlula ku-oxidation, incishiswe, futhi i-hydrolysis ukuze ikhiqize i-rifampicin sodium.

Imininingwane

Into	Imininingwane
Indawo yokubilisa	700.89°C (isilinganiso esilinganiselwe)
Ubuningi	1.2387 (isilinganiso esilinganiselwe)
Indawo yokuncibilika	179-181°C (Disemba)
i-pKa	3.85±0.70 (Kubikezelwe)
ukumelana	1.6630 (isilinganiso)
Izimo zokugcina	Isiqandisi -20°C

Isicelo

I-Rifamycin S isetshenziswa njengesidakamizwa esiphakathi kwemithi ukuvimbela umsebenzi we-RNA polymerase yamagciwane. Ivimbela ukwakheka kwe-RNA yamagciwane, ekugcineni ivimbele ukwakheka kwamaprotheni adingwa yibhaktheriya, okuholela ekufeni kwamagciwane futhi ibonise imiphumela yokubulala amagciwane.