izindaba

I-Hyaluronic acid iyi-polysaccharide enkulu yama-molecule ekhishwe ku-bovine vitreous humor ngoprofesa be-ophthalmology base-Columbia University uMeyer noPalmer ngo-1934. Isixazululo sayo samanzi sicacile futhi sifana nengilazi. Kamuva, kwatholakala ukuthi i-hyaluronic acid ingenye yezingxenye eziyinhloko ze-human extracellular matrix kanye ne-intercellular matrix, kanye nokugcwalisa phakathi kwamaseli, edlala indima ebalulekile ekubumbeni, esakhiweni, kanye nasekusebenzeni kwesikhumba. Ukuguga, imibimbi, kanye nokugoba komzimba womuntu kuhlobene eduze nokwehla kokuqukethwe kwe-hyaluronic acid esikhumbeni.

Ngokwesakhiwo, i-hyaluronic acid iwukujiya kwezinto ezimbili eziphuma ku-glucose, futhi ngokuphindaphinda lesi sakhiwo ngokuphindaphindiwe, iba i-hyaluronic acid. Lokhu kufana kakhulu nesakhiwo sama-polysaccharide amaningi, ngakho-ke i-sodium hyaluronateinomsebenzi ofanayo nama-polysaccharide amaningi - ukuthambisa.

Kodwai-hyaluronic acidayizinzile. Ngokuvamile, i-hyaluronic acid ikhona ngesimo sayo sikasawoti we-sodium. Ngokusho kwezisindo zama-molecule ezahlukene, i-hyaluronic acid ingahlukaniswa ibe yisisindo sama-molecule aphezulu, isisindo sama-molecule esimaphakathi, isisindo sama-molecule esiphansi, kanye ne-oligomeric hyaluronic acid. Ngokukhethekile, umenzi ngamunye unesigaba esifanayo sesisindo sama-molecule se-sodium hyaluronate.I-UNILONGungumkhiqizi ochwepheshe we-sodium hyaluronate, okuhlanganisa ibanga lezimonyo, ibanga lokudla, i-sodium hyaluronate yebanga lezemithi kanye nezinyei-sodium hyaluronatei-UNILONG ihlukanisa i-sodium hyaluronate kanje:

◆I-hyaluronic acid enesisindo sama-molecule aphezulu: I-hyaluronic acid inesisindo sama-molecule esingaphezu kuka-1500KDa, esingakha ifilimu ephefumulayo ebusweni besikhumba, sivale umswakama ebusweni besikhumba, sivimbele ukuhwamuka komswakama, futhi sinikeze umswakama wesikhathi eside. Kodwa ayinawo umoya omuhle futhi ngeke imuncwe yisikhumba.

◆ I-hyaluronic acid enesisindo sama-molecule esimaphakathi: I-hyaluronic acid inesisindo sama-molecule esiphakathi kuka-800KDa no-1500KDa futhi ingakha ifilimu ephefumulayo ebusweni besikhumba, ivale umswakama futhi iqinise isikhumba.

◆I-hyaluronic acid enesisindo esiphansi sama-molecule: I-hyaluronic acid inesisindo sama-molecule esiphakathi kuka-10KDa no-800KDa futhi ingangena engqimbeni yesikhumba. Idlala indima ngaphakathi kwesikhumba, ivale umswakama, ikhuthaze ukugaywa kwesikhumba, futhi yenze isikhumba sibe manzi, sibushelelezi, sibe mnene, sithambe, futhi sinwebeke. Amandla okuvimbela ukuhwamuka kwamanzi aphansi.

◆ I-Oligo hyaluronic acid: Ama-molecule e-hyaluronic acid anesisindo sama-molecule esingaphansi kwe-10KDa, okungukuthi izakhiwo ze-monosaccharide ezingaphansi kwama-50 kanye nezinga le-polymerization elingaphansi kwama-25, angangena ngokujulile engqimbeni ye-dermis futhi abe nemiphumela ephelele neqhubekayo yokuthambisa. Ngokungafani nama-molecule avamile e-hyaluronic acid anemiphumela yokuthambisa ebusweni besikhumba, anesikhathi eside sokuthambisa, imiphumela emihle, ukusetshenziswa kwesikhathi eside, ukulwa nokuguga, kanye nemiphumela yokususa imibimbi.

Amanye ama-asidi e-hyaluronic angase aguqulwe ngokwesakhiwo (i-acetylation, njll.) ukuze abe nobungane kakhulu esikhumbeni. Ama-asidi e-hyaluronic ajwayelekile ayancibilika emanzini, kodwa ukusondelana kwawo nesikhumba akwanele. Ngemva kokuguqulwa, anganamathela kahle esikhumbeni.

Uma unemibuzo noma izidingo mayelana ne-sodium hyaluronate, sicela ukhululeke ukungitshelaxhumana ne-Unilongnganoma yisiphi isikhathi.