I-Tolfenamic acid CAS 13710-19-5

I-CAS:13710-19-5

I-Molecular Formula:I-C14H12ClNO2

Isisindo se-Molecular:261.7

I-EINECS:237-264-3

Omqondofana:I-LABOTEST-BB LT00772313; I-TOLFENAMIC ACID; 2-(3-chloro-2-methylphenyl)amino)-benzoicaci;n-(2-methyl-3-chlorophenyl)anthranilicacid; 2-(3-CHLORO-O-TOLUIDINO)BENZOIC ACID; 2 (3-CHLORO-2-METHYLANILINO)BENZOIC ACID; 2-[(3-CHLORO-2-METHYLPHENYL)AMINO]BENZOIC ACID; I-Tolfedine; 2-[(3-Chloro-o-tolyl)amino]benzoic acid; n-(3-chloro-o-tolyl)-anthranilicaci; I-CLOTAM; n-(3-chloro-o-tolyl) -anthranilicacid

Shiya Umlayezo Wakho

Imininingwane Yomkhiqizo

Landa

Omaka bomkhiqizo

Iyini i-Tolfenamic acid CAS 13710-19-5?

I-Tolfenamic acid iyisidakamizwa esingeyona i-steroidal eqeda ukuvuvukala esetshenziswa kabanzi emtholampilo njenge-antipyretic, i-analgesic, ne-anti-inflammatory drug. Iphuma ku-ortho aminobenzoic acid, i-Tolfenamic acid, eyakhiwe yi-GEA eDenmark. Inemiphumela eqinile yokunqanda ukuvuvukala kanye ne-analgesic enemiphumela engemihle emincane.

Ukucaciswa

Into	Ukucaciswa
Iphuzu elibilayo	405.4±40.0 °C(Kubikezelwe)
Ukuminyana	1.2037 (isilinganiso esinzima)
MW	261.7
pKa	3.66±0.36(Okubikezelwe)
EINECS	223-123-3
Iphuzu elibilayo	405.4±40.0 °C(Kubikezelwe)

Isicelo

I-Tolfenamic acid inemiphumela yayo ye-antipyretic ne-analgesic ngokuvimbela ukukhiqizwa kwe-cyclooxygenase. Njengamanje, isetshenziswa kakhulu ekwelapheni izifo ezifana ne-rheumatoid arthritis kanye ne-migraine ekusebenzeni komtholampilo. Eminyakeni yamuva nje, izazi zasekhaya nakwamanye amazwe zenze izifundo ezihlukahlukene ngalokhu futhi zathola ukuthi i-Tolfenamic acid idlala indima ebalulekile ekuvimbeleni ukukhula kwamangqamuzana e-tumor, ilawule i-tumor cell apoptosis, iphazamise ukubonakaliswa kwamangqamuzana e-tumor, ilawule ukusebenza kwe-oncogenes kanye ne-tumor suppressor genes, futhi ivimbele i-tumor angiogenesis.