I-SHIKONIN CAS 517-89-5 Shikonine

CAS:517-89-5

amagama afanayo:

5,8-Dihydroxy-2-[(R) -1-hydroxy-4-methyl-3-pentenyl] -1,4-naphthalenedione;TokyoViolet;(R) -5,8-Dihydroxy-2-(1-hydroxy -4-Methylpent-3-zu-1-yl)naphthalene-1,4Chemicalbook-dione;SHIKONIN(AS);Shikonin,froMArnebiasp.;(-)-ShikoninChina;Shikonine;Shikonin5,8-Dihydroxy-2-[(1R) )-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione

Igama Brand: Unilong
Indawo Yomsuka: Shandong, China
Ubumsulwa:99%

Igama lomkhiqizo:SHIKONIN

Ukupakisha: 25kgs / isigubhu

Ukulethwa:Ngokushesha

MF:C16H16O5

MW:288.3

Shiya Umlayezo Wakho

Imininingwane Yomkhiqizo

Landa

Omaka bomkhiqizo

YiniSHIKONIN

Ikristalu yenaliti onsundu onsundu, indawo encibilikayo engu-147℃, ukuzungezisa okubonakalayo αD20=+135°(benzene). Incibilika ku-phenethyl ether, i-acetone, i-chloroform, i-methanol, i-ethanol, i-glycerol, amafutha ezilwane nemifino kanye nezixazululo ze-alkaline ezinamanzi, ezingancibiliki emanzini. Imibala iyashintsha ngenani le-Ph, inani le-Ph lika-4-6 libebomvu, inani le-Ph lika-8 libe nsomi, futhi inani le-Ph lika-10-12 libe luhlaza okwesibhakabhaka. Ukumelana nokukhanya okuhle, ukumelana nokushisa nokumelana ne-oxidation, okungazinzile ekwehliseni umthamo, kanye nokunsomi okumnyama uma kwenzeka kuma-ion ensimbi. Inomphumela othile we-antibacterial.

Ukucaciswa kweSHIKONIN

I-CAS	517-89-5
Amanye Amagama	Shikonine
Ukubukeka	impushana onsomi
Ubumsulwa	99%
Umbala	onsomi
Isitoreji	Isitoreji Esomisiwe Esipholile
Iphakheji	25kg/isikhwama
Isicelo	Ukudla

Isicelo seSHIKONIN

(1) Umphumela we-Hypoglycemic Ukukhishwa kweqabunga le-comfrey kanye ne-polysaccharide (A, B, C) ye-comfrey kunomphumela osobala we-hypoglycemic.

(2) Umphumela we-bacteriostatic i-Lithospermum unomphumela ovimbelayo kugciwane le-Jingke 68-1 in vitro, futhi unomphumela ovimbelayo ku-Staphylococcus aureus. Umphumela we-anti-parainfluenza virus we-levoshikonin wacwaningwa ngokusabela kwe-hemagglutination kanye nendlela ye-cytopathic. Imiphumela yabonisa ukuthi inobuthi obuphansi phakathi kwebanga lokuhlushwa elisetshenziswe ocwaningweni, futhi inomsebenzi othile wegciwane le-in vitro anti-influenza kanye nokubulawa okuqondile kwegciwane le-parainfluenza. umphumela.

(3) Imithelela ekuhlanganiseni kwegazi: Umjovo we-intraperitoneal wezingxenye ze-shikonin (i-shikonin, i-acetylshikonin) akuphazamisi isikhathi sokuhlangana kwegazi, kodwa ungavimbela umphumela we-anticoagulant we-heparin.

(4) Umthelela we-Anti-tumor Ukukhishwa kwe-Comfrey kunomphumela othile ovimbelayo esigabeni sakamuva (isigaba se-G2) sokuhlanganiswa kwe-DNA kumaseli e-Hela.

(5) Umthelela we-Antitumor u-Shikonin uvimbela ukwanda, uthuthukisa i-apoptosis futhi unxenxa ukuboshwa komjikelezo weseli emigqeni yeseli ye-choriocarcinoma engazweli emthini womuntu (i-JAR/MTX) ethuthukisiwe. Ukuhlola kubonisa ukuthi ukugcwala kwe-shikonin kuyanda ngomthamo. Futhi ukwelulwa kwesikhathi sesenzo, izinga lokuvinjelwa lokukhula kwamangqamuzana amelana nomuthi we-choriocarcinoma nalo lenyuke kakhulu.

6 akukho mehluko obalulekile uma kuqhathaniswa neqembu lokulawula elihle. ezahlukene. Kubonisa ukuthi i-shikonin ingavimbela umsebenzi we-hypothalamic-pituitary-gonadal axis kumagundane.

(7) Umphumela we-Antioxidant Abanye abacwaningi balinganisa ikhono lokukhipha i-shikonin ku-superoxide radical (O2-) kanye ne-1,1-diphenyl-2-picrophenhydrazine radical (DPPH), kanye nomthelela wayo ku-β- - Ukuvinjelwa kwe-carotene/linoleic acid autoxidation uhlelo. Imiphumela yabonisa ukuthi i-shikonin inamandla okukhukhula aqinile ku-DPPH kanye ne-O2-, futhi yayinomphumela osobala wokuvimbela kusistimu ye-auto-oxidation ye-β-carotene/linoleic acid. Umthamo onamandla we-antioxidant.