I-SHIKONIN CAS 517-89-5 Shikonine

I-CAS: 517-89-5

amagama afanayo：

5,8-Dihydroxy-2-[(R)-1-hydroxy-4-methyl-3-pentenyl]-1,4-naphthalenedione;TokyoViolet;(R)-5,8-Dihydroxy-2-(1-hydroxy-4-Methylpent-3-en-1-yl)naphthalene-1,4Chemicalbook-dione;SHIKONIN(AS);Shikonin,froMAarnebiasp.;(-)-ShikoninChina;Shikonin;Shikonin5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione

Igama lomkhiqizo: Unilong
Indawo Yomsuka: Shandong, China
Ubumsulwa: 99%

Igama lomkhiqizo: SHIKONIN

Ukupakisha: 25kgs/isigubhu

Ukulethwa: Ngokushesha

MF:C16H16O5

I-MW:288.3

Shiya Umlayezo Wakho

Imininingwane Yomkhiqizo

Landa

Amathegi Omkhiqizo

KuyiniI-SHIKONIN

Ikristalu yenaliti ephuzi-nsundu, iphuzu lokuncibilika elingu-147℃, ukujikeleza okubonakalayo okungu-αD20=+135°(benzene). Incibilika ku-phenethyl ether, i-acetone, i-chloroform, i-methanol, i-ethanol, i-glycerol, uwoyela wezilwane nemifino kanye nezixazululo zamanzi ze-alkaline, ayincibiliki emanzini. Umbala uyashintsha ngenani le-Ph, ngenani le-Ph elingu-4-6 elibomvu, inani le-Ph elingu-8 elinsomi, kanye nenani le-Ph elingu-10-12 eliluhlaza okwesibhakabhaka. Ukumelana okuhle kokukhanya, ukumelana nokushisa kanye nokumelana ne-oxidation, okungazinzile ekunciphiseni umthamo, kanye nobomvu omnyama uma kwenzeka ama-ion ensimbi. Inomphumela othile wokulwa namagciwane.

Imininingwane yeI-SHIKONIN

I-CAS	517-89-5
Amanye Amagama	I-Shikonine
Ukubukeka	impuphu ensomi
Ubumsulwa	99%
Umbala	onsomi
Isitoreji	Isitoreji Esomile Esipholile
Iphakheji	25kg/isikhwama
Isicelo	Ukudla

Ukusetshenziswa kweI-SHIKONIN

(1) Umphumela we-Hypoglycemic I-comfrey ekhishwe eqabungeni kanye ne-polysaccharide (A, B, C) ye-comfrey inomphumela osobala we-hypoglycemic.

(2) Umphumela we-bacteriostatic I-Lithospermum inomphumela wokuvimbela igciwane le-Jingke 68-1 in vitro, futhi inomphumela wokuvimbela i-Staphylococcus aureus. Umphumela wegciwane le-levoshikonin wokulwa ne-parainfluenza wafundwa ngokusabela kwe-hemagglutination kanye nendlela ye-cytopathic. Imiphumela ibonise ukuthi yayinobuthi obuphansi ngaphakathi kobubanzi bokuhlushwa obusetshenziswe ocwaningweni, futhi yayinomsebenzi othile wegciwane lokulwa ne-influenza in vitro kanye nokubulawa ngqo kwegciwane le-parainfluenza.

(3) Imiphumela ekujiyeni kwegazi: Ukujova kwezingxenye ze-shikonin ngaphakathi kwesisu (shikonin, acetylshikonin) akusithinti isikhathi sokujiya kwegazi, kodwa kungavimbela umphumela we-heparin wokulwa nokujiya kwegazi.

(4) Umphumela wokulwa nomdlavuza I-Comfrey extract inomphumela othile wokuvimbela esigabeni sokugcina (isigaba se-G2) sokwenziwa kwe-DNA kumaseli e-Hela.

(5) Umphumela wokulwa nomdlavuza I-Shikonin ivimbela ukwanda, ikhuthaza i-apoptosis futhi ibangela ukuboshwa komjikelezo weseli emigqeni yamaseli amelana nemithi ye-choriocarcinoma yabantu (JAR/MTX) ekhuliswe ngaphakathi kwe-vitro. Ukuhlolwa kubonisa ukuthi ukuhlushwa kwe-shikonin kuyanda ngomthamo. Futhi ukwelulwa kwesikhathi sokusebenza, izinga lokuvinjelwa kokukhula kwamaseli amelana nemithi ye-choriocarcinoma nakho kwanda kakhulu.

(6) Imiphumela ekukhiqizweni kwama-hormone Umphumela we-shikonin emsebenzini we-hypothalamic-pituitary-gonadal axis kumagundane abesifazane asebekhulile ukhombisile ukuthi amazinga e-serum hormone eqenjini le-shikonin ayephansi kakhulu kunalawo eqenjini lokulawula elibi, futhi bekungekho mehluko obalulekile uma kuqhathaniswa neqembu lokulawula elihle. Kubonisa ukuthi i-shikonin ingavimbela umsebenzi we-hypothalamic-pituitary-gonadal axis kumagundane.

(7) Umphumela we-Antioxidant Abanye abacwaningi balinganise ikhono lokuqopha le-shikonin ku-superoxide radical (O2-) kanye ne-1,1-diphenyl-2-picrophenhydrazine radical (DPPH), kanye nomphumela walo ku-β- - Ukuvinjelwa kohlelo lwe-carotene/linoleic acid autooxidation. Imiphumela ikhombisile ukuthi i-shikonin inekhono elinamandla lokuqopha i-DPPH kanye ne-O2-, futhi yayinomphumela osobala wokuvimbela ohlelweni lwe-auto-oxidation lwe-β-carotene/linoleic acid. Amandla aqinile e-antioxidant.